Phosphopyruvate hydratase complex
WebStructure. ENO3 is one of three enolase isoforms, the other two being ENO1 (ENO-α) and ENO2 (ENO-γ). Each isoform is a protein subunit that can form hetero-or homodimers of the following combinations: αα, αβ, αγ, ββ, and γγ.. Gene. The ENO3 gene spans 6 kb and contains 12 exons, though the first exon is an untranslated region and, thus, non-coding. . … WebAconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis ...
Phosphopyruvate hydratase complex
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WebApr 28, 2014 · In vitro co-immunoprecipitation studies in prostate cancer cell extracts demonstrated that these compounds disrupted the HIF-1α/p300 complex. The downstream effects of inhibiting the HIF-1α/p300 interaction were evaluated by determining HIF-1α target gene expression at the mRNA and protein levels. WebFeb 1, 2011 · Phosphopyruvate hydratase activity Specific Function Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). Pfam Domain Function Enolase_C ( PF00113) Enolase_N ( PF03952)
http://amigo.geneontology.org/amigo/term/GO:0000015 Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is: 2-phospho-D-glycerate See more In humans there are three subunits of enolase, α, β, and γ, each encoded by a separate gene that can combine to form five different isoenzymes: αα, αβ, αγ, ββ, and γγ. Three of these isoenzymes (all homodimers) are … See more Using isotopic probes, the overall mechanism for converting 2-PG to PEP is proposed to be an E1cB elimination reaction involving a carbanion intermediate. The following detailed mechanism is based on studies of crystal structure and See more Small-molecule inhibitors of enolase have been synthesized as chemical probes (substrate-analogues) of the catalytic mechanism of the enzyme and more recently, have been investigated as potential treatments for cancer and infectious diseases. … See more Enolase is a member of the large enolase superfamily. It has a molecular weight of 82,000-100,000 Daltons depending on the isoform. In human alpha enolase, the two subunits are See more In recent medical experiments, enolase concentrations have been sampled in an attempt to diagnose certain conditions and their severity. For example, higher concentrations of … See more • Holt A, Wold F (December 1961). "The isolation and characterization of rabbit muscle enolase". The Journal of Biological Chemistry. 236 (12): … See more • Enolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more
WebDiscovered an efficient Pt-catalyzed hydroboration of complex molecules. ... "The First Example of a Nitrile Hydratase Model Complex that Reversibly Binds Nitriles" Journal of … WebOct 25, 2024 · The upper fraction without viral dsRNA in both strains increased the GagPol amount and downregulated a phosphopyruvate hydratase Eno1 and regulator of the Fps1 glycerol channel Ask10. 3.6. STRINGAnalysis. Differentially expressed proteins, ... Molecular complex detection (MCODE) clustering algorithm located four hubs of highly …
WebAug 13, 2024 · eno; phosphopyruvate hydratase cl21457 Location:70 → 525 TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate …
Webphosphopyruvate hydratase complex Complete GO annotation on QuickGO Phenotypes & Variants Variants Structure 3D structure databases AlphaFoldDB B5VSR2 SMR B5VSR2 … chunk to decode word listWebA hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its … detect silverlight usageWebphosphopyruvate hydratase complex. Ontology. cellular_component. Synonyms. enolase complex. Alternate IDs. None. Definition. A multimeric enzyme complex, usually a dimer … chunk totsWebPredicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. ... Predicted to be part of phosphopyruvate hydratase complex. Orthologous to human ENO4 (enolase 4). Genome Resources. Alliance ; Gene:558487 ; VEGA:OTTDARG00000038661 ; Ensembl(GRCz11):ENSDARG00000070598 ; Note None … chunk tomatoesWebFeb 1, 2011 · Phosphopyruvate hydratase activity Specific Function Appears to have a function in striated muscle development and regeneration. Pfam Domain Function Enolase_C ( PF00113) Enolase_N ( PF03952) Transmembrane Regions Not Available Cellular Location Cytoplasm Gene sequence detect sd card in monitorWebJul 5, 2005 · Phosphopyruvate hydratase; catalyzes the hydrolysis of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; localized to mitochondria and vacuoles View computational annotations Molecular Function Manually Curated enables melatonin binding ( IDA ) chunk toonWebAbstract. Inactivation of the von Hippel–Lindau tumor-suppressor protein (pVHL) is the signature “truncal” event in clear cell renal cell carcinoma, which is the most common … detect slide and slipe train