Hif genecard

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August undefined, 2024

WebPathology [ edit] Von Hippel–Lindau syndrome (VHL) is a dominantly inherited hereditary cancer syndrome predisposing to a variety of malignant and benign tumors of the eye, brain, spinal cord, kidney, pancreas, and adrenal glands. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. Web7 de abr. de 2024 · 通过搜索文献和TCMSP数据库收集一贯煎成分及靶点, GeneCard、OMIM数据库收集肝纤维化疾病靶点. 基于STRING数据库构建一贯煎-肝纤维化蛋白互作子网络, 应用重启随机游走算法获得一贯煎治疗肝纤维化的关键基因, 通过基因本体富集分析与京都基因和基因组百科全书通路分析关键基因主要参与的生物学 ...

EPAS1 - Wikipedia

Web7 de fev. de 2011 · p16Ink4a is a protein involved in regulation of the cell cycle. Currently, p16Ink4a is considered a tumor suppressor protein because of its physiological role and downregulated expression in a ... Web24 de mai. de 2024 · 1.2 疾病相关靶点检索以“prostatitis”为关键词,分别在GeneCard（https: ... TNF、Toll样受体信号通路信号通路与炎症免疫调控，氧化损伤相关[23]；HIF-1 信号通路在炎症因子调控及低氧浓度或缺氧应答中发挥重要作用的；PI3K-AKT信号通路在某些病毒复制过程中 ... dfe heat warning

Hypoxia compromises the mitochondrial metabolism of …

Web17 linhas · 27 de mar. de 2024 · The Human Gene Database. GeneCards is a … WebEndothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is … WebClassicamente, a Hipercolesterolemia Familiar (HF) foi descrita como doença de herança autossômica dominante, caracterizada por elevação do colesterol total e do LDL-c, … churchwell fire

TiPARP forms nuclear condensates to degrade HIF-1α and …

Web21 de mar. de 2024 · HIF3A (Hypoxia Inducible Factor 3 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF3A include Erythrocytosis, Familial, 4 and … WebEPAS1. Endothelial PAS domain-containing protein 1 ( EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is a type of hypoxia-inducible factor, a group of transcription factors involved in the physiological response to oxygen concentration. dfe health educationWeb3 de abr. de 2024 · This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy … churchwell group atlanta

"WebHealth Insurance Fund (HIF) is an Australian, not-for-profit insurer. In 1954 it was brought into existence as the WA Government Employee's Hospital and Medical Benefits Fund Incorporated. But has since undergone a series of name changes to better reflect the scope and services it provides. " - Hif genecard

Hif genecard

HIF1A hypoxia inducible factor 1 subunit alpha [ (human)]

Web15 de abr. de 2024 · In normoxia, Hif genes are constitutively transcribed and translated, but the resultant protein is degraded by the proteasome through oxygen-dependent … WebNational Center for Biotechnology Information

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WebHypoxia-inducible factor. Hypoxia-inducible factors ( HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. [1] [2] They are only present in parahoxozoan animals. [3] WebOverexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding …

Web21 de mar. de 2024 · HIF1AN (Hypoxia Inducible Factor 1 Subunit Alpha Inhibitor) is a Protein Coding gene. Diseases associated with HIF1AN include Erythrocytosis, Familial, … Web25 de nov. de 2024 · Furthermore, HIF-1α can support NF-κB pathway activation by driving IKKβ gene transcription through a hypoxia response element present in the promoter and, at the same time, by directly inducing p65 (77, 78). Conversely, it has been reported that NF-κB can induce HIF-1α by binding directly to the HIF-1α promoter (79, 80).

WebHypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix protein that activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, … Web维普中文期刊服务平台，是重庆维普资讯有限公司标准化产品之一，本平台以《中文科技期刊数据库》为数据基础，通过对国内出版发行的15000余种科技期刊、7000万篇期刊全文进行内容组织和引文分析，为高校图书馆、情报所、科研机构及企业用户提供一站式文献服务。

WebConsequently, the placenta provides an excellent model for understanding the relationship between hypoxia (low O2 tension), organogenesis (organ development)and …

Web24 de mai. de 2004 · The earliest observations linking p300 and CBP to cancer were studies in leukemias, where chromosome translocations disrupt the CBP gene. The first to be characterized was the t (8,16) (p11,p13 ... dfe healthy eatingWebThe prolyl hydroxylase domain (PHD) / hypoxia-inducible factor (HIF) axis is a critically important oxygen-sensing pathway that mediates tissue adaptation to low oxygen environments primarily via the transcriptional regulation of gene expression. The laboratory of Volker H. Haase investigates the key components of this pathway and their ... dfe heatwave guidance for schoolsWeb네임스페이스. 기사; 토론; 더 dfe heatwave adviceWeb维普期中文期刊服务平台，由维普资讯有限公司出品，通过对国内出版发行的14000余种科技期刊、5600万篇期刊全文进行内容分析和引文分析，为专业用户提供一站式文献服务：全文保障，文献引证关系，文献计量分析；并以期刊产品为主线、其它衍生产品或服务做补充，方便专业用户、机构用户在 ... dfe heated lithium batteriesWebHIF-1α содержит базовую область спираль-петля-спираль (helix-loop-helix) рядом с C-концом, за которой следуют два разных домена PAS (PER-ARNT-SIM) и PAC (PAS … dfe heat adviceWeb1 de jun. de 2024 · The TiPARP nuclear bodies recruit both HIF-1α and an E3 ubiquitin ligase HUWE1, which promotes the ubiquitination and degradation of HIF-1α. Similarly, … dfe heat wave guidanceWeb16 de jun. de 2024 · By suppressing HIF-1α and other oncogenic transcription factors, TiPARP exerts strong antitumor effects both in cell culture and in mouse xenograft … dfe heatwave school guidance