WebJan 8, 2024 · Background: Currently, the accepted standard management of limited-stage small cell lung cancer (SCLC) is concurrent chemoradiotherapy (CCRT), but the frequency of radiotherapy is controversial. Therefore, this meta-analysis, which compared the efficacy and toxicity between twice-daily (BID) and once-daily (OD) CCRT, was performed to … WebAug 1, 2024 · Results. Five RCTs with a total of 1941 patients (OD vs. BID) were included. The relative risk (RR) for OS and PFS was 0.97 (CI95% 0.8–1.1, p = 0.731) and 0.90 (CI95% 0.7–1.1, p = 0.20) at 3-years.In the metaregression analysis, hypofractionated radiotherapy schedules were associated with an improvement in overall survival (p = …
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